GHK-Cu Copper Peptide
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, a peptide first isolated from human plasma albumin. It is classed as a research peptide and cosmetic ingredient and has been studied in cell culture, gene-expression and tissue-remodelling models. GHK-Cu is supplied as a lyophilised (freeze-dried) powder in a sealed vial, in 50 mg and 100 mg sizes, priced RM 100–120. No certificate of analysis has been published for the batch on sale yet, so no purity figure is claimed on this page. Ships within 2 working days of payment. Sold for laboratory research use only, not for human or veterinary use.
Research use only. Sold for laboratory research only. Not for human or veterinary use, not for consumption, and not a medicine, food or cosmetic.
- Ships within 2 working days of payment.
- Free shipping across Malaysia.
- Pay by FPX online banking.
Certificates of analysis
No certificate of analysis has been published for the batch on sale yet, so this page makes no purity claim. Each certificate will name the testing laboratory, the batch, the test date and the method.
GHK-Cu specifications
| Also known as | Copper tripeptide-1, Glycyl-L-histidyl-L-lysine copper(II), Prezatide copper, Copper peptide |
|---|---|
| Form | Lyophilised (freeze-dried) powder in a sealed vial |
| Sizes | 50 mg · 100 mg |
| CAS number | 89030-95-5 |
| Molecular formula | C14H23CuN6O4+ |
| Molecular weight | 402.92 g/mol |
| Sequence | GHK (Gly-His-Lys) |
| PubChem | CID 71587328 |
| Storage (sealed) | -20 °C (supplier listing and insert: stable for at least 4 years as a solid; Cayman item is the acetate salt) |
| Storage (reconstituted) | Supplier insert does not recommend storing the aqueous solution for more than one day |
What research says about GHK-Cu
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, a peptide first isolated from human plasma albumin. It is classed as a research peptide and cosmetic ingredient and has been studied in cell culture, gene-expression and tissue-remodelling models.
GHK binds Cu(2+) with high affinity, and reviews report that GHK-Cu changes expression of many genes linked to tissue remodelling, collagen and glycosaminoglycan synthesis, and inflammatory and antioxidant pathways.
Investigational as a research peptide; supporting literature is mostly reviews, and several of the cited reviews are by the group that discovered GHK.
Cited studies
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The review reported that GHK-Cu stimulates collagen, elastin and glycosaminoglycan synthesis and nerve and vessel outgrowth in models, and that gene-expression data suggest multiple regulated pathways.
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.. Int J Mol Sci, 2018. doi:10.3390/ijms19071987 · PubMed 29986520
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The review described GHK and GHK-Cu as increasing collagen, elastin and growth-factor synthesis and fibroblast and keratinocyte proliferation, with anti-inflammatory effects reported in models.
The human tri-peptide GHK and tissue remodeling.. J Biomater Sci Polym Ed, 2008. doi:10.1163/156856208784909435 · PubMed 18644225
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The review summarised antioxidant, anti-inflammatory and gene-regulating actions of GHK-Cu and proposed it as a candidate for study in age-associated neurodegeneration.
The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health.. Oxid Med Cell Longev, 2012. doi:10.1155/2012/324832 · PubMed 22666519
Handling and storage
- Sealed vial
- -20 °C (supplier listing and insert: stable for at least 4 years as a solid; Cayman item is the acetate salt)
- After reconstitution
- Supplier insert does not recommend storing the aqueous solution for more than one day
Shipping, returns and payment
Dispatch. Ships within 2 working days of payment.
Shipping. Free shipping across Malaysia. Peninsular Malaysia 1–4 working days; Sabah, Sarawak and Labuan 3–7 working days.
Returns. No change-of-mind returns; a wrong or damaged item is replaced or refunded. Nothing here affects your rights under the Consumer Protection Act 1999.
Payment. FPX online banking.
Questions
- Is there a certificate of analysis for GHK-Cu?
Not yet for the batch on sale. When one is published it appears in the certificates table on this page with the laboratory, batch, test date, method and result. See how to read a certificate of analysis.
- How is GHK-Cu stored?
Sealed: -20 °C (supplier listing and insert: stable for at least 4 years as a solid; Cayman item is the acetate salt). After reconstitution: Supplier insert does not recommend storing the aqueous solution for more than one day. These are supplier figures, cited in the handling section.
